Retail supply chains span the globe to provide consumers with an infinite range of products each day. With billions of unique item and location combinations to manage, these supply chains are complex, diverse, and ubiquitous. Given the scale and scope of their operations, costly and unpredictable imbalances of inventory or capacity can plague retailers and suppliers. However, a solution to this fundamental challenge is what we call the retail media-enhanced supply chain that continuously re-balances localized supply and demand.